What does the 'four core genotypes' mouse model tell us about sex differences in the brain and other tissues? Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction. PLoS Biol 7 Nat Neurosci 10 BMC Res Notes 8: The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. PLoS One 8 8:
Hum Mol Genet 7 4: PLoS Genet 11 Four core genotypes mouse model: Two Y genes can replace the entire Y chromosome for assisted reproduction in the mouse. Genes Brain Behav 7 6: Does Rbmy have a role in sperm development in mice? Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. Cardiovasc Res 3: Front Neuroendocrinol 30 1: PLoS Genet 10 6: Hum Mol Genet 25 J Neurosci 22 J Exp Med 5: Mouse models for evaluating sex chromosome effects that cause sex differences in non-gonadal tissues. Arterioscler Thromb Vasc Biol 35 8: PLoS Biol 7 Sex chromosome complement regulates habit formation. A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits. PLoS One 8 8: PLoS One 11 1: The y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice. Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction. Sex differences in juvenile mouse social behavior are influenced by sex chromosomes and social context. Sex chromosomes and brain sexual differentiation. The expression of Y-linked Zfy2 in XY mouse oocytes leads to frequent meiosis 2 defects, a high incidence of subsequent early cleavage stage arrest and infertility. A new deletion of the mouse Y chromosome long arm associated with the loss of Ssty expression, abnormal sperm development and sterility.
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